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Involvement in medical research studies

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Lawley, the Pharmaceutical Company behind the hormone creams AndroForte, AndroFeme and ProFeme are continually involved with clinical trials and hormone & medical research studies.

It’s a vital aspect of medical advancement and this includes the field of hormone replacement therapy. Hormone replacement therapy is one of the fastest growing areas of medicine in 2014. The market share revenue is in the $billions and is continuing to grow daily.

A little background on Lawley

Lawley are based in Perth Australia and use an approved government facility to manufacture their hormone creams. AndroForte, AndroFeme and ProFeme are pharmaceutical grade bioidentical topical creams that treat low testosterone (in men and women) and progesterone deficiency/estrogen dominance (in women). The Lawley mission is to encourage people to treat natural hormone deficiencies with natural bioidentical hormone therapies, rather than synthetic therapies. Treating “like with like” means that the body absorbs and reacts better to the therapy. Ultimately, the body sees the therapy as an extension and top up for its current natural hormone production, rather than a synthetic treatment that can further stifle the body’s own level of natural hormone production. Participating in medical research studies is an important way of showcasing this theory.

The reach of hormone replacement therapies like testosterone replacement therapy reaches far beyond the framework of sexual dysfunction, low libido and menopause.

Current Research and Clinical Trials

Depression:

A trial on testosterone antidepressant augmentation in Women

(Involvement: Assoc Prof Karen K Miller MD Harvard Medical School, Neuroendocrine Unit, Massachusetts General Hospital, Boston, USA.)

Alzheimer’s:

A controlled trial to determine the efficacy of testosterone as a strategy to prevent the development of Alzheimer’s Disease.

(Involvement: Professors Ralph Martins and Roger Clarnette, The McCusker Alzheimer Disease Research Foundation, Inc., Perth, Australia.)

IVF:

A trial to determine the use of transdermal testosterone cream in IVF pre-treatment and its effect on controlled ovarian stimulation and IVF outcome in poor responder IVF patients:

(Involvement: Dr Shlomi Barak, Melbourne IVF, East Melbourne, Department of Obstetrics and Gynecology, University of Melbourne.)

Menopause:

A study into the effects of testosterone and oestradiol therapy on clinical indicators and biomarkers of dry eye in post-menopausal women.

(Involvement: Professor Fiona Stapleton, School of Optometry and Vision Science, University of NSW, Sydney, Australia)

Recently Completed Research and Clinical Trials

  • The effect of AndroFeme on post-menopausal women with low libido.
  • The pharmacokinetics of AndroForte compared to AndroGel (TestoGel) on men with low testosterone.
  • The role of Testosterone on ΑΒ Deposition of Alzheimer’s disease.
  • Effect of sequential transdermal progesterone cream on endometrium, bleeding pattern, and plasma progesterone and salivary progesterone levels in postmenopausal women.
  • Distribution and metabolism of topically applied progesterone in a rat model.
  • Plasma and saliva concentrations of progesterone in pre- and postmenopausal women after topical application of progesterone cream.
  • Long-term pharmacokinetics and clinical efficacy of ANDROMEN®FORTE 5% cream for androgen replacement in hypogonadal men.
  • Transdermal testosterone therapy improves well-being, mood, and sexual function in pre-menopausal women.
  • The pharmacokinetics pilot study of AndroFeme 1% testosterone in testosterone deficient women.
  • A double-blind, randomized, placebo-controlled trial of the effect of testosterone cream on the sexual motivation of menopausal hysterectomized women with hypoactive sexual desire disorder.
  • Pharmacokinetics Of Andromen Forte 5% Cream: A Dose Finding Study.

 

For more information on Lawley hormone skin creams and their involvement in medical research studies you can visit the Lawley site.

 

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